Coming upTue 24 Nov 2026,
MRI-guided holmium-166 transarterial radioembolization: Technical advancements and clinical considerations
Tiny radioactive beads guided into liver tumours using MRI scans, and whether they can safely deliver higher doses of radiation.
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The defense
From the Radboud University agenda
- When
- Tue 24 Nov 2026, 90 min
- Where
- Radboud University, NetherlandsFaculty of Medical Sciences (Radboudumc)
- Fields
- Supervisors
- Co-supervisors
- Language
- English
- Stream
- Stream link not yet announced
A doctoral defense is public: anyone may watch.
About the thesis
Transarterial radioembolization delivers radioactive microspheres through the hepatic artery to target liver tumours while preserving healthy tissue. This thesis examines how adaptive, MRI-guided techniques can refine the therapy.
The research introduced an administration device for controlled microsphere delivery and an MRI quantification method to evaluate particle distribution and absorbed doses during treatment. Analyses emphasized the need for homogeneous radiation across tumours and provided insights into subsequent lung injury. Furthermore, an initial study in four patients with primary liver cancer showed that MRI-guided treatment safely enabled higher radiation doses than standard care, encouraging further development of personalized radioembolization.
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Listed from the Radboud University agenda.